Event Name: NIBGE-1601
Event Code : NIBGE-1601
Trade Name: NIBGE Double Gene Cotton
Crop: Gossypium hirsutum L. - Cotton
Developer: National Institute for Biotechnology and Genetic Engineering (Pakistan)
Method of Trait Introduction: Agrobacterium tumefaciens-mediated plant transformation
GM Trait: Lepidopteran insect resistance
Commercial Trait: (Stacked) Insect Resistance (IR)
Basic Genetic Modification
| Gene Introduced | Gene Source | Product | Function |
| cry1Ac | Bacillus thuringiensis subsp. Kurstaki strain HD73 | Cry1Ac delta-endotoxin | confers resistance to lepidopteran insects by selectively damaging their midgut lining |
| cry2Ab2 | Bacillus thuringiensis subsp. kumamotoensis | Cry2Ab delta-endotoxin | confers resistance to lepidopteran insects by selectively damaging their midgut lining |
Regulatory Approvals: Country, Year and Type of Approval
| Country | Food direct use or processing |
Feed direct use or processing |
Cultivation domestic or non-domestic use |
| Pakistan |
Last updated: April 10, 2026
Documents and Links
Regulatory and Biosafety Information
The GM Approval Database, or GMAD, is one of ISAAA’s unique features that compiles all the available information about biotech/GM crops that have been approved for planting and importation for food and feed, and commercialization. ISAAA sources out the information from publicly available decision documents per country, Biosafety Clearing Houses and peer-reviewed scholarly articles to maintain the credibility of the database. Your contribution can help expand and maintain the GMAD and make useful information more available to researchers, students, and the general public. You can help by donating as little as $10.