Developer:
Bayer CropScience (including fully and partly owned companies)

Method of Trait Introduction:
Conventional breeding - cross hybridization and selection involving transgenic donor(s)

GM Trait s :
Glufosinate herbicide tolerance , Glyphosate herbicide tolerance , Lepidopteran insect resistance , Antibiotic resistance

Commercial Trait:
(Stacked)  Herbicide Tolerance + Insect Resistance

Summary of Basic Genetic Modification

Gene Introduced	Gene Source	Product	Function
2mepsps	Zea mays	5-enolpyruvyl shikimate-3-phosphate synthase enzyme (double mutant version)	decreases binding affinity for glyphosate, thereby increasing tolerance to glyphosate herbicide
cry1Ab	Bacillus thuringiensis subsp. kurstaki	Cry1Ab delta-endotoxin	confers resistance to lepidopteran insects by selectively damaging their midgut lining
cry2Ae	Bacillus thuringiensis subsp Dakota	Cry2Ae delta-endotoxin	confers resistance to lepidopteran insects by selectively damaging their midgut lining
bar	Streptomyces hygroscopicus	phosphinothricin N-acetyltransferase (PAT) enzyme	eliminates herbicidal activity of glufosinate (phosphinothricin) herbicides by acetylation
vip3A(a)	Bacillus thuringiensis strain AB88	VIP3A vegetative insecticidal protein	confers resistance to feeding damage caused by lepidopteran insects by selectively damaging their midgut lining
aph4 (hpt)  *	Escherichia coli	hygromycin-B phosphotransferase (hph) enzyme	allows selection for resistance to the antibiotic hygromycin B

 * : Selection Marker/Reporter  

Summary of Regulatory Approvals: Country, Year and Type of Approval

Country	Food direct use or processing	Feed direct use or processing	Cultivation domestic or non-domestic use
Australia
Brazil
Japan
Mexico
Philippines
South Korea
Taiwan

 

Regulatory and Biosafety Information

• CIB - Brazil
• FAO GM Foods Platform (Mexico)
• INVIMA - Colombia
• Japan Biosafety Clearing House
• Japan Biosafety Clearing House
• Korea Biosafety Clearing House
• Office of the Gene Technology Regulator - Australia
• Taiwan Food and Drug Administration