Species: White crucian carp (Carassius auratus civieri)

Country of 1st Author: China
Year: 2019

Institute	Hunan Normal University Changsha 410081 CN
Editing Method	Embryo edit
SDN Type	SDN-1
Delivery	Cas9 mRNA (300 ng µL-1) plus the gRNA (30 ng µL-1) of tyr gene was co-microinjected into one-cell embryos
Foreign DNA	No
Undergone Regulatory Process	No

Target Gene(s)

Gene Name	Gene Trait	Trait Category	NGT	Methods/Remarks
TYR Tyrosinase	Pigmentation - melanin reduction	Colour	CRISPR Cas9 (spCas9)

References, Documents, and Links

• Targeted disruption of tyrosinase causes melanin reduction in Carassius auratus cuvieri and its hybrid progeny