Species: Common Carp (Cyprinus carpio)

Country of 1st Author: China
Year: 2019

Breed Strain	Oujiang color common carp (Cyprinus carpio var. color)
Institute	Shanghai Ocean University Shanghai 201306 CN
Editing Method	Embryo edit
SDN Type	SDN-1
Delivery	The sgRNA and Cas9 protein were co-injected into the one-cell embryos
Foreign DNA	No
Undergone Regulatory Process	No

Target Gene(s)

Gene Name	Gene Trait	Trait Category	NGT	Methods/Remarks
ASIP 1 Agouti Signaling Protein	[ASIP function]	Colour	CRISPR Cas9 (spCas9)	Pigmentation.
ASIP 2 Agouti-signaling protein	ASIP Function	Colour	CRISPR Cas9 (spCas9)	Pigmentation. n the present study, we first investigated the formation of black pattern in economical fish by disrupting the ASIP gene in Oujiang color common carp through CRISPR/Cas-mediated genome editing. The results revealed that the ASIP gene might be involved in regulating melanin aggregation and distribution during black patch formation in Oujiang color common carp

References, Documents, and Links

• ASIP disruption via CRISPR/Cas9 system induces black patches dispersion in Oujiang color common carp