Species: Cattle (Bos taurus)

Country of Determination: Brazil
Year: 2021

Breed Strain	Beef
Commercial Name	PRLR-SLICK beef cattle
Developer	Acceligen Inc. Eagan, MN US
Editing Method	Embryo edit
SDN Type	SDN-1
Foreign DNA	No
Undergone Regulatory Process	Yes

Target Gene(s)

Gene Name	Gene Trait	Trait Category	NGT	Methods/Remarks
PRLR Prolactin Receptor	This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.	Abiotic Stress	CRISPR Cas9 (spCas9)

Regulatory Documents and Links