Gene Editing Used to Develop Vitamin A-fortified RiceNovember 20, 2019
Genome editing could be an alternative approach to improve the vitamin A content of crops, according to a study by Akira Endo and colleagues at the National Agriculture and Food Research Organization and Ishikawa Prefectural University in Japan. The results of the study are published in Rice.
Beta-carotene, a precursor of vitamin A, is a vital target for biofortification of crops to aiming to address the problem of vitamin A deficiency prevalent in developing countries. In a previous study, it was reported that dominant expression of splicing variants in the Orange (Or) gene causes beta-carotene accumulation in cauliflower curd. In Endo and team's study, they focused on rice's Orange gene (Osor) and tested if they could increase the beta-carotene content of rice callus using CRISPR-Cas9. The transformed calli turned orange, indicating hyper-accumulation of beta-carotene. Molecular analyses indicated that orange-colored calli are caused by an abundance of in-frame aberrant Osor transcripts, while out-of-frame mutation was not associated with orange color.
Based on the findings, the researchers concluded that directed gene modification of Osor gene using CRISPR-Cas9-mediated genome editing leads to beta-carotene fortification in rice calli. This presents an alternative approach to improving beta-carotene accumulation in crops.
Read the research article in Rice.
You might also like:
See more articles:
News from Around the World
- Experts Use Microparticles to Fortify Foods with Nutrients
- Verdeca's HB4® Drought and Herbicide Tolerant Soybeans Get Approval in Paraguay
- Biotechnology Gets Attention at Senate of the Philippines
- SEARCA BIC's Agri-biotech Boot Camp Puts the Spotlight on Youth in Agriculture
- Experts Unlock Key to Photosynthesis
- Resistance Genes for Deadly Ash Tree Disease Discovered
- 'Designer' Plants Developed to Combat Environmental Challenges
- Scientists Investigate Plant Nodule and Lateral Roots, Gain Another Step to Developing Self-Fertilizing Crops
Plant Breeding Innovations
- Gene Editing Used to Develop Vitamin A-fortified Rice
- Biotech Expert Panel: CRISPR Technology Can Transform Agricultural Production
Subscribe to CBU: