Lactobacillus diolivorans Produces High Value- Chemicals from Crude Glycerol


Societies have been trying to shift away from fossil fuels and towards renewable resources. Since biodiesel production isn't as economical as it can be, to find use for the crude glycerol waste from it would be of major importance.

Katharina Anna Lindlbauer of the University of Natural Resources and Life Sciences in Austria tested the production of 3-hydroxypropionaldehyde (3-HPA), from biodiesel-derived crude glycerol by Lactobacillus diolivorans.

The team also overcame potential limitations of glycerol transport into the cell by overexpressing the glycerol uptake facilitating protein, PduF, to maximize the cells' capability of producing 3-HPA. This resulted in a significant increase of glycerol conversion.

Lactobacillus diolivorans proved to be a valuable cell factory for the use of crude glycerol in producing high-value chemicals like 3-HPA.


This article is part of the Crop Biotech Update, a weekly summary of world developments in agri-biotech for developing countries, produced by the Global Knowledge Center on Crop Biotechnology, International Service for the Aquisition of Agri-Biotech Applications SEAsiaCenter (ISAAA)

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