Gene Editing Supplement

In 2021, researchers at the Massachusetts Institute of Technology's McGovern Institute for Brain Research discovered and characterized Cas7-11, the first CRISPR enzyme that makes precise, guided cuts to RNA strands without harming cells in the process. Now, with collaborators at the University of Tokyo, the same team reveals that Cas7-11 can be shrunk to a more compact version, making it an even more viable option for editing the RNA inside living cells.

Rice With More Resistant Starch Made Possible Using CRISPR-Cas9

Using CRISPR-Cas9, researchers from Texas A&M University were able to produce rice with an increased amount of resistant starch. The findings can help develop rice that is more beneficial for human health and possibly reduce the risk of diet-related chronic diseases.

Experts Enhance Editing Rates of CRISPR-Cas12a

Scientists from the University of Massachusetts Chan Medical School reported the increased gene editing rate of Cas12a nucleases to almost 100%. Their findings, published in GEN Biotechnology journal, could improve the use of Cas12a to uncover functions of new genes and design new CRISPR-based treatments.

CRISPR SWAPnDROP Enables Efficient Large-Scale Interspecies Gene Transfer

Researchers from the Synthetic Microbiology Center Marburg in Germany presented a versatile scarless and marker-free genome editing system in their latest publication in Nature Communications. CRISPR SWAPnDROP can perform indels consecutively or in parallel and transfer chromosomal regions between species of independent size and with high-editing efficiencies.

Research and Tools

Public Acceptance and Engagement

Experts Discuss Addressing Public Acceptance of CRISPR in Agriculture and Medicine

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