Event Name: NK603 x T25 x DAS40278
Event Code : MON-ØØ6Ø3-6 x ACS-ZMØØ3-2 x DAS-40278-9
Trade Name: Roundup Ready™ Liberty Link™ Enlist™ Maize
Crop: Zea mays L. - Maize, Corn
Developer: Dow AgroSciences LLC and DuPont (Pioneer Hi-Bred International Inc.)
Method of Trait Introduction: Conventional breeding - cross hybridization and selection involving transgenic donor(s)
GM Traits: Glufosinate herbicide tolerance , Glyphosate herbicide tolerance , Antibiotic resistance , 2,4-D herbicide tolerance
Commercial Trait: (Stacked) Herbicide Tolerance (HT)
Basic Genetic Modification
| Gene Introduced | Gene Source | Product | Function |
| cp4 epsps (aroA:CP4) | Agrobacterium tumefaciens strain CP4 | herbicide tolerant form of 5-enolpyruvulshikimate-3-phosphate synthase (EPSPS) enzyme | decreases binding affinity for glyphosate, thereby conferring increased tolerance to glyphosate herbicide |
| pat (syn) | synthetic form of pat gene derived from Streptomyces viridochromogenes strain Tu 494 | phosphinothricin N-acetyltransferase (PAT) enzyme | eliminates herbicidal activity of glufosinate (phosphinothricin) herbicides by acetylation |
| bla * | Escherichia coli | beta lactamase enzyme | detoxifies beta lactam antibiotics such as ampicillin |
| aad-1 | synthetic form of the aad-1 gene from Sphingobium herbicidovorans | aryloxyalkanoate dioxygenase 1 (AAD-1) protein | detoxifies 2,4-D herbicide by side-chain degradation and degrades the R-enantiomers of aryloxyphenoxypropionate herbicides |
Regulatory Approvals: Country, Year and Type of Approval
| Country | Food direct use or processing |
Feed direct use or processing |
Cultivation domestic or non-domestic use |
| Argentina | |||
| Brazil | |||
| Colombia | |||
| European Union | |||
| Paraguay |
Last updated: November 15, 2023
Documents and Links
Event Description
Regulatory and Biosafety Information
The GM Approval Database, or GMAD, is one of ISAAA’s unique features that compiles all the available information about biotech/GM crops that have been approved for planting and importation for food and feed, and commercialization. ISAAA sources out the information from publicly available decision documents per country, Biosafety Clearing Houses and peer-reviewed scholarly articles to maintain the credibility of the database. Your contribution can help expand and maintain the GMAD and make useful information more available to researchers, students, and the general public. You can help by donating as little as $10.