Developer:
Monsanto Company (including fully and partly owned companies)

Method of Trait Introduction:
Agrobacterium tumefaciens-mediated plant transformation

GM Trait s :
Lepidopteran insect resistance , Antibiotic resistance

Commercial Trait:
(Singular)  Insect Resistance

Summary of Basic Genetic Modification

Gene Introduced	Gene Source	Product	Function
cry1Ac	Bacillus thuringiensis subsp. Kurstaki strain HD73	Cry1Ac delta-endotoxin	confers resistance to lepidopteran insects by selectively damaging their midgut lining
nptII  *	Escherichia coli Tn5 transposon	neomycin phosphotransferase II enzyme	allows transformed plants to metabolize neomycin and kanamycin antibiotics during selection
aad  *	Escherichia coli	3''(9)-O-aminoglycoside adenylyltransferase enzyme	allows selection for resistance to aminoglycoside antibiotics such as spectinomycin and streptomycin

 * : Selection Marker/Reporter  

Summary of Regulatory Approvals: Country, Year and Type of Approval

Country	Food direct use or processing	Feed direct use or processing	Cultivation domestic or non-domestic use
Argentina
Australia
Brazil
Canada
China
Colombia
Costa Rica
European Union
India
Japan
Mexico
New Zealand
Pakistan
Paraguay
Philippines
Singapore
South Africa
South Korea
Sudan
Taiwan
United States of America

 

Event Description

• CBD Biosafety Clearing House
• CERA GM Crop Database

Regulatory and Biosafety Information

• Agri-Food and Veterinary Authority of Singapore
• AVA - Approved GMOs Singapore
• Brazil CTNBio
• Canadian Food Inspection Agency
• Center for Environmental Risk Assessment
• CIB - Brazil
• European Food Safety Authority
• Food Standards Australia New Zealand
• Japan Biosafety Clearing House
• Office of the Gene Technology Regulator - Australia
• Taiwan Food and Drug Administration
• US Department of Agriculture - APHIS
• US Food and Drug Administration
• US Food and Drug Administration

Detection Methods

• EU Reference Laboratory for GM Food and Feed
• GMO Detection Method Database