COT102 x MON15985 | GM Approval Database- ISAAA.org

Event Name: COT102 x MON15985

Event Code : SYN-IR1Ø2-7 x MON-15985-7
Trade Name: Bollgard® III

Crop: Gossypium hirsutum L. - Cotton

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Developer:
Monsanto Company (including fully and partly owned companies)

Method of Trait Introduction:
Conventional breeding - cross hybridization and selection involving transgenic donor(s)

GM Trait s :
Lepidopteran insect resistance , Antibiotic resistance , Visual marker

Commercial Trait:
(StackedInsect Resistance

Summary of Basic Genetic Modification

Gene Introduced Gene Source Product Function
vip3A(a) Bacillus thuringiensis strain AB88 VIP3A vegetative insecticidal protein confers resistance to feeding damage caused by lepidopteran insects by selectively damaging their midgut lining
aph4 (hpt)  * Escherichia coli hygromycin-B phosphotransferase (hph) enzyme allows selection for resistance to the antibiotic hygromycin B
cry1Ac Bacillus thuringiensis subsp. Kurstaki strain HD73 Cry1Ac delta-endotoxin confers resistance to lepidopteran insects by selectively damaging their midgut lining
cry2Ab2 Bacillus thuringiensis subsp. kumamotoensis Cry2Ab delta-endotoxin confers resistance to lepidopteran insects by selectively damaging their midgut lining
nptII  * Escherichia coli Tn5 transposon neomycin phosphotransferase II enzyme allows transformed plants to metabolize neomycin and kanamycin antibiotics during selection
aad  * Escherichia coli 3''(9)-O-aminoglycoside adenylyltransferase enzyme allows selection for resistance to aminoglycoside antibiotics such as spectinomycin and streptomycin
uidA  * Escherichia coli beta-D-glucuronidase (GUS) enzyme produces blue stain on treated transformed tissue, which allows visual selection


 * : Selection Marker/Reporter  

Summary of Regulatory Approvals: Country, Year and Type of Approval

Country Food
direct use or processing
Feed
direct use or processing
Cultivation
domestic or non-domestic use
Australia      
Japan      
Mexico      

Last updated: February 19, 2015