Event Name: 7Crp#10
Event Code : not available
Trade Name: not available
Crop: Oryza sativa L. - Rice
Developer: National Institute of Agrobiological Sciences (Japan)
Method of Trait Introduction: Agrobacterium tumefaciens-mediated plant transformation
GM Traits: Anti-allergy , Antibiotic resistance
Commercial Trait: (Singular) Modified Product Quality (PQ)
Basic Genetic Modification
| Gene Introduced | Gene Source | Product | Function |
| 7crp | synthetic form of tolerogenic protein from Cryptomeria japonica | modified cry j 1 and cry j 2 pollen antigens containing seven major human T cell epitopes | triggers mucosal immune tolerance to cedar pollen allergens |
| aph4 (hpt) * | Escherichia coli | hygromycin-B phosphotransferase (hph) enzyme | allows selection for resistance to the antibiotic hygromycin B |
Regulatory Approvals: Country, Year and Type of Approval
No approvals found
Documents and Links
Event Description
- Article: A rice-based edible vaccine expressing multiple T cell epitopes induces oral tolerance for inhibition of Th2-mediated IgE responses
- Article: A rice-based edible vaccine expressing multiple T-cell epitopes to induce oral tolerance and inhibit allergy
- Article: Development of transgenic rice seed accumulating a major Japanese cedar pollen allergen (Cry j 1) structurally disrupted for oral immunotherapy
- CBD Biosafety Clearing House
Regulatory and Biosafety Information
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