Event Name: TC1507 x MON810 x NK603
Event Code : DAS-Ø15Ø7-1 x MON-ØØ81Ø-6 x MON-ØØ6Ø3-6
Trade Name: Optimum™ Intrasect
Crop: Zea mays L. - Maize, Corn
Developer: DuPont (Pioneer Hi-Bred International Inc.)
Method of Trait Introduction: Conventional breeding - cross hybridization and selection involving transgenic donor(s)
GM Traits: Glufosinate herbicide tolerance , Glyphosate herbicide tolerance , Lepidopteran insect resistance
Commercial Trait: (Stacked) Herbicide Tolerance (HT) + Insect Resistance (IR)
Basic Genetic Modification
| Gene Introduced | Gene Source | Product | Function |
| cry1Fa2 | synthetic form of cry1F gene derived from Bacillus thuringiensis var. aizawai | modified Cry1F protein | confers resistance to lepidopteran insects by selectively damaging their midgut lining |
| cry1Ab | Bacillus thuringiensis subsp. kurstaki | Cry1Ab delta-endotoxin | confers resistance to lepidopteran insects by selectively damaging their midgut lining |
| pat | Streptomyces viridochromogenes | phosphinothricin N-acetyltransferase (PAT) enzyme | eliminates herbicidal activity of glufosinate (phosphinothricin) herbicides by acetylation |
| cp4 epsps (aroA:CP4) | Agrobacterium tumefaciens strain CP4 | herbicide tolerant form of 5-enolpyruvulshikimate-3-phosphate synthase (EPSPS) enzyme | decreases binding affinity for glyphosate, thereby conferring increased tolerance to glyphosate herbicide |
Regulatory Approvals: Country, Year and Type of Approval
| Country | Food direct use or processing |
Feed direct use or processing |
Cultivation domestic or non-domestic use |
| Argentina | |||
| Brazil | |||
| Canada | |||
| Colombia | |||
| European Union | |||
| Iran | |||
| Japan | |||
| Mexico | |||
| Paraguay | |||
| Philippines | |||
| South Africa | |||
| South Korea | |||
| Taiwan | |||
| Uruguay |
* point mouse arrow over year for notes
Last updated: October 20, 2023
Documents and Links
Event Description
Regulatory and Biosafety Information
- Brazil - Conselho de Informacoes sobre Biotecnologia (CIB)
- Bureau of Plant Industry - Philippines
- DA - Bureau of Plant Industry
- Japan Biosafety Clearing House
- Taiwan Food and Drug Administration
- USDA GAIN Report - South Africa 2015
Detection Methods
The GM Approval Database, or GMAD, is one of ISAAA’s unique features that compiles all the available information about biotech/GM crops that have been approved for planting and importation for food and feed, and commercialization. ISAAA sources out the information from publicly available decision documents per country, Biosafety Clearing Houses and peer-reviewed scholarly articles to maintain the credibility of the database. Your contribution can help expand and maintain the GMAD and make useful information more available to researchers, students, and the general public. You can help by donating as little as $10.