Event Name: MON15985
Event Code : MON-15985-7
Trade Name: Bollgard II™ Cotton
Crop: Gossypium hirsutum L. - Cotton
Developer: Monsanto Company (including fully and partly owned companies)
Method of Trait Introduction: Microparticle bombardment of plant cells or tissue
GM Traits: Lepidopteran insect resistance , Antibiotic resistance , Visual marker
Commercial Trait: (Stacked) Insect Resistance (IR)
Basic Genetic Modification
| Gene Introduced | Gene Source | Product | Function |
| cry1Ac | Bacillus thuringiensis subsp. Kurstaki strain HD73 | Cry1Ac delta-endotoxin | confers resistance to lepidopteran insects by selectively damaging their midgut lining |
| nptII * | Escherichia coli Tn5 transposon | neomycin phosphotransferase II enzyme | allows transformed plants to metabolize neomycin and kanamycin antibiotics during selection |
| aad * | Escherichia coli | 3''(9)-O-aminoglycoside adenylyltransferase enzyme | allows selection for resistance to aminoglycoside antibiotics such as spectinomycin and streptomycin |
| uidA * | Escherichia coli | beta-D-glucuronidase (GUS) enzyme | produces blue stain on treated transformed tissue, which allows visual selection |
| cry2Ab2 | Bacillus thuringiensis subsp. kumamotoensis | Cry2Ab delta-endotoxin | confers resistance to lepidopteran insects by selectively damaging their midgut lining |
Regulatory Approvals: Country, Year and Type of Approval
| Country | Food direct use or processing |
Feed direct use or processing |
Cultivation domestic or non-domestic use |
| Australia | |||
| Brazil | |||
| Burkina Faso | |||
| Canada | |||
| China | |||
| Colombia | |||
| Costa Rica | |||
| European Union | |||
| India | |||
| Japan | |||
| Kenya | |||
| Malaysia | |||
| Mexico | |||
| New Zealand | |||
| Nigeria | |||
| Philippines | |||
| Singapore | |||
| South Africa | |||
| South Korea | |||
| Taiwan | |||
| United States | |||
| Vietnam |
* point mouse arrow over year for notes
Last updated: August 11, 2024
Documents and Links
Event Description
Regulatory and Biosafety Information
- Agri-Food and Veterinary Authority of Singapore
- Agri-Food and Veterinary Authority of Singapore
- Bureau of Plant Industry - Philippines
- Canadian Food Inspection Agency
- CBD Biosafety Clearing House
- Food Standards Australia New Zealand
- GEAC Biosafety Data of Approved GM crops
- India Biosafety Clearing House Decision
- Japan Biosafety Clearing House
- Malaysia Biosafety Clearing House
- NOTICE OF APPROVAL FOR ENVIRONMENTAL RELEASE AND PLACING ON THE MARKET - Kenya
- Office of the Gene Technology Regulator - Australia
- Office of the Gene Technology Regulator - Australia
- Singapore Food Agency
- Taiwan Food and Drug Administration
- US Department of Agriculture - APHIS
- US Food and Drug Administration
- US Food and Drug Administration
- USDA-FAS GAIN Report - China 2018
- USDA-FAS GAIN Report - India 2018
Detection Methods
The GM Approval Database, or GMAD, is one of ISAAA’s unique features that compiles all the available information about biotech/GM crops that have been approved for planting and importation for food and feed, and commercialization. ISAAA sources out the information from publicly available decision documents per country, Biosafety Clearing Houses and peer-reviewed scholarly articles to maintain the credibility of the database. Your contribution can help expand and maintain the GMAD and make useful information more available to researchers, students, and the general public. You can help by donating as little as $10.