Event Name: 3006-210-23 x 281-24-236 x MON88913 x COT102 x DAS81910
Event Code : DAS-21Ø23-5 x DAS-24236-5 x MON-88913-8 x SYN-IR1Ø2-7 x DAS-81910-7
Trade Name: not available
Crop: Gossypium hirsutum L. - Cotton
Developer: Dow AgroSciences LLC
Method of Trait Introduction: Conventional breeding - cross hybridization and selection involving transgenic donor(s)
GM Traits: Glufosinate herbicide tolerance , Glyphosate herbicide tolerance , Lepidopteran insect resistance , Antibiotic resistance , 2,4-D herbicide tolerance
Commercial Trait: (Stacked) Herbicide Tolerance (HT) + Insect Resistance (IR)
Basic Genetic Modification
| Gene Introduced | Gene Source | Product | Function |
| cry1Ac | Bacillus thuringiensis subsp. Kurstaki strain HD73 | Cry1Ac delta-endotoxin | confers resistance to lepidopteran insects by selectively damaging their midgut lining |
| vip3A(a) | Bacillus thuringiensis strain AB88 | VIP3A vegetative insecticidal protein | confers resistance to feeding damage caused by lepidopteran insects by selectively damaging their midgut lining |
| cry1F | Bacillus thuringiensis var. aizawai | Cry1F delta-endotoxin | confers resistance to lepidopteran insects by selectively damaging their midgut lining |
| aph4 (hpt) * | Escherichia coli | hygromycin-B phosphotransferase (hph) enzyme | allows selection for resistance to the antibiotic hygromycin B |
| cp4 epsps (aroA:CP4) | Agrobacterium tumefaciens strain CP4 | herbicide tolerant form of 5-enolpyruvulshikimate-3-phosphate synthase (EPSPS) enzyme | decreases binding affinity for glyphosate, thereby conferring increased tolerance to glyphosate herbicide |
| pat | Streptomyces viridochromogenes | phosphinothricin N-acetyltransferase (PAT) enzyme | eliminates herbicidal activity of glufosinate (phosphinothricin) herbicides by acetylation |
| aad-12 | Delftia acidovorans | aryloxyalkanoate di-oxygenase 12 (AAD-12) protein | catalyzes the side chain degradation of 2,4-D herbicide |
Regulatory Approvals: Country, Year and Type of Approval
| Country | Food direct use or processing |
Feed direct use or processing |
Cultivation domestic or non-domestic use |
| Brazil | |||
| Colombia | |||
| Japan | |||
| Mexico | |||
| South Korea |
Last updated: October 18, 2023
Documents and Links
Regulatory and Biosafety Information
The GM Approval Database, or GMAD, is one of ISAAA’s unique features that compiles all the available information about biotech/GM crops that have been approved for planting and importation for food and feed, and commercialization. ISAAA sources out the information from publicly available decision documents per country, Biosafety Clearing Houses and peer-reviewed scholarly articles to maintain the credibility of the database. Your contribution can help expand and maintain the GMAD and make useful information more available to researchers, students, and the general public. You can help by donating as little as $10.