Gene Editing Supplement

A team of researchers from the University of Cordoba in Spain used CRISPR gene editing technology to study the complexities of nitrogen metabolism in beans, revealing promising insights that could help enhance agricultural sustainability.

Scientists Use Gene Editing to Combat Tomato Leaf Curl New Delhi Virus

A study published in the Journal of Phytopathology demonstrates the efficacy of the CRISPR-Cas9 system in enhancing the resistance of tomato plants against tomato leaf curl New Delhi virus (ToLCNDV).

Fewer Off-Target Gene Editors Using AI

Artificial intelligence (AI) is being applied to gene editing to create more precise and effective tools, similar to its impact on drug development. While CRISPR-Cas9 revolutionized the field, off-target effects and genomic rearrangements remain a concern, especially for in vivo therapies. Other gene editing technologies like ZFNs and TALENs also face challenges, highlighting the need for advancements that AI is now poised to address. An article in Genetic Engineering and Biotechnology News tackles some advances in gene editing involving AI.

Scientists Review RNAi-induced Effects in GM Plants

Experts from Fraunhofer Institute for Molecular Biology and Applied Ecology and partners in Germany conducted a review to classify mechanisms of RNA interference (RNAi) effects induced by short interfering RNA from different sources in plants and to identify technologies that can be used to detect these effects. The review paper is published in the Frontiers in Plant Science.

Research and Tools

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