Event Name: NK603 x MON810 x 4114 x MIR604
Event Code : MON-00603-6 x MON-00810-6 x DP004114-3 x SYN-IR604-4
Trade Name: Not available
Crop: Zea mays L. - Maize, Corn
- Basic Information
- Authorizations
- Documents and Links
Developer:
Syngenta and Monsanto Company
Method of Trait Introduction:
Conventional breeding - cross hybridization and selection involving transgenic donor(s)
GM Trait
s
:
Glufosinate herbicide tolerance
,
Glyphosate herbicide tolerance
,
Coleopteran insect resistance
,
Lepidopteran insect resistance
,
Antibiotic resistance
,
Mannose metabolism
Commercial Trait:
(Stacked)
Herbicide Tolerance
+
Insect Resistance
Summary of Basic Genetic Modification
| Gene Introduced | Gene Source | Product | Function |
| cp4 epsps (aroA:CP4) | Agrobacterium tumefaciens strain CP4 | herbicide tolerant form of 5-enolpyruvulshikimate-3-phosphate synthase (EPSPS) enzyme | decreases binding affinity for glyphosate, thereby conferring increased tolerance to glyphosate herbicide |
| cry1Ab | Bacillus thuringiensis subsp. kurstaki | Cry1Ab delta-endotoxin | confers resistance to lepidopteran insects by selectively damaging their midgut lining |
| cry1F | Bacillus thuringiensis var. aizawai | Cry1F delta-endotoxin | confers resistance to lepidopteran insects by selectively damaging their midgut lining |
| cry34Ab1 | Bacillus thuringiensis strain PS149B1 | Cry34Ab1 delta-endotoxin | confers resistance to coleopteran insects particularly corn rootworm by selectively damaging their midgut lining |
| cry35Ab1 | Bacillus thuringiensis strain PS149B1 | Cry35Ab1 delta-endotoxin | confers resistance to coleopteran insects particularly corn rootworm by selectively damaging their midgut lining |
| pat | Streptomyces viridochromogenes | phosphinothricin N-acetyltransferase (PAT) enzyme | eliminates herbicidal activity of glufosinate (phosphinothricin) herbicides by acetylation |
| goxv247 * | Ochrobactrum anthropi strain LBAA | glyphosate oxidase | confers tolerance to glyphosate herbicides by degrading glyphosate into aminomethylphosphonic acid (AMPA) and glyoxylate |
| nptII * | Escherichia coli Tn5 transposon | neomycin phosphotransferase II enzyme | allows transformed plants to metabolize neomycin and kanamycin antibiotics during selection |
| pmi * | Escherichia coli | Phosphomannose Isomerase (PMI) enzyme | metabolizes mannose and allows positive selection for recovery of transformed plants |
* : Selection Marker/Reporter
Summary of Regulatory Approvals: Country, Year and Type of Approval
| Country | Food direct use or processing |
Feed direct use or processing |
Cultivation domestic or non-domestic use |
| Canada | |||
| Colombia | |||
| Japan | |||
| South Korea | |||
| Taiwan |
* point mouse arrow over year for notes
Last updated: March 2, 2017
Regulatory and Biosafety Information
- Canadian Food Inspection Agency
- INVIMA - Colombia
- Korean Biosafety Clearing House
- Taiwan Food and Drug Administration
Last updated: January 12, 2013


